Pananatiling Aktibo para sa Kalusugan ng Kasukasuan Impormasyon

This is the clinical evidence summary written for health professionals. It is technical, and it lists the research this page was built from. You do not need to read it to understand your treatment or to make a decision about it.

Overview

• There is little evidence that physical activity is associated with significant harm [1].
• The benefits of physical activity, in general, outweigh the risks [1].
• Maintenance interventions may help people continue to be physically active [2].
• Maintenance interventions may improve physical function and health-related quality of life [2].
• The 2018 US physical activity guidelines recognised that any bouts of physical activity count for health [3].
• ISPAH's Eight Investments That Work for Physical Activity provides a summary of eight areas for action supported by scientific evidence [4].
• ISPAH's Eight Investments That Work for Physical Activity has worldwide applicability [4].
• In children and adolescents aged 6-17, participating in moderate to vigorous physical activities led to multiple positive health outcomes [5].
• The 2020 WHO guidelines on physical activity and sedentary behaviour update previous WHO recommendations released in 2010 [9].
• About 15 times more physical activity of at least moderate intensity is needed to achieve similar results regarding incident cardiovascular disease [17].
• RCTs have failed to provide conclusive evidence that physical activity causes a reduced risk of death [18].
• Changes to physical activity guidelines, such as removal of a 10-min bout criterion, pose challenges for physical activity surveillance [44].
• At follow-up, 65.0% of inactive participants were taking part in sport [46].
• At follow-up, 85.6% of inactive participants were meeting recommended MVPA guidelines [46].
• Most differences in functional outcomes from scapular exercise programs did not reach the minimum threshold to be considered clinically important [48].
• Individuals not achieving the WHO guideline for physical activity showed an elevated risk of cancer, even if they were abdominally lean [49].
• The hazard ratio for elevated cancer risk in individuals not achieving the WHO guideline for physical activity, even if abdominally lean, was 1.04 (95% CI 1.01 to 1.07) [49].

How It Works

• There is little evidence that physical activity is associated with significant harm, and the benefits generally outweigh the risks [1].
• Maintenance interventions may help people continue to be physically active and improve physical function and health-related quality of life [2].
• ISPAH's Eight Investments That Work for Physical Activity provides a summary of eight areas for action that are supported by scientific evidence and have worldwide applicability [4].
• Light-intensity physical activity accounts for the majority of physical activity energy expenditure (51–59%) [6].
• Sustained physical activity in older age is associated with improved overall health [7].
• Exercise interventions implemented at ≤12 weeks after total knee arthroplasty primarily improved functional performance [10].
• Exercise interventions lasting >12 weeks after total knee arthroplasty resulted in greater gains in muscle strength and joint flexibility [10].
• The proportion of participants meeting health-enhancing physical activity recommendations increased from 33.1% to 42.3% between baseline and first follow-up in the Allez Hop programme [12].
• The addition of wearable activity tracker use did not have any effect on perceived joint function or health-related quality of life in people with hip and knee osteoarthritis [14].
• Aquatic exercise appears to provide meaningful pain relief for musculoskeletal disorders, with benefits that may persist during follow-up [15].
• Moderate treadmill exercise following an initial period of short-term immobilization has a positive impact on tendon-bone interface healing after anterior cruciate ligament reconstruction in a murine model [19].
• Prolonged immobilization has a detrimental effect on physical recovery after anterior cruciate ligament reconstruction in a murine model [19].
• Small increases in non-occupational physical activity in inactive adults are associated with substantial protection against a range of chronic disease outcomes [20].
• The ProPASS consortium aims to produce evidence on the associations of physical activity, sitting, and sleep with long-term health outcomes and longevity [21].
• Consensus statements outline approaches that may identify determinants and modifiers of cardiorespiratory fitness exercise response [22].
• Not all daily metabolic equivalent task units (METs) are the same in their health benefits [23].
• Pain science education may act as a mechanism of action for exercise interventions for people with knee or hip osteoarthritis [25].
• Pain science education is less successful when delivered standalone for people with knee or hip osteoarthritis [25].
• Findings question whether total hip arthroplasty should be prioritized only for patients with severe hip osteoarthritis symptoms [26].
• Pain is modulated by many factors, and the relationship between pain and tissue becomes less predictable the longer pain persists [27].

What the Evidence Shows

• There is little evidence that physical activity is associated with significant harm, and the benefits, in general, outweigh the risks [1].
• There is moderate certainty evidence that fall prevention exercise programmes are likely to be cost-effective [11].
• Much of the evidence regarding physical activity and ageing is based on longitudinal associations from observational and randomised controlled intervention studies, as well as quantitative and qualitative social studies in relatively healthy community-dwelling older adults [13].
• Participants in the NMC programme found it to be less physically challenging but more enjoyable and potentially of more benefit compared with control players [16].
• About 15 times more physical activity of at least moderate intensity is needed to achieve similar results regarding the joint associations of device-measured physical activity and abdominal obesity with incident cardiovascular disease [17].
• Randomised controlled trials have failed to provide conclusive evidence that physical activity causes a reduced risk of death [18].
• Exercise may improve pain and function in knee osteoarthritis with low to moderate certainty, but it is uncertain whether differences are clinically important [29].
• Protocols using painful exercises offer a small but significant benefit over pain-free exercises in the short term, with moderate quality of evidence [30].
• A school-based intervention resulted in a significant group-by-time interaction for mean minutes of moderate-to-vigorous physical activity per day in favour of the intervention group (adjusted difference between groups at follow-up=3.85 min, 95% CI (0.79 to 6.91), p≤0.01) [31].
• The school-based intervention included significantly more vigorous physical activity (2.45 min, p≤0.01), equating to 27 min more moderate-to-vigorous physical activity per week [31].
• There was no significant effect of an augmented exercise referral scheme using web-based behavioural support on weekly moderate-to-vigorous physical activity at 12 months between the groups recorded in ≥10 min bouts (mean difference 11.8 min of MVPA, 95% CI: −2.1 to 26.0; p=0.10) [33].
• There was no significant effect of an augmented exercise referral scheme using web-based behavioural support on weekly moderate-to-vigorous physical activity at 12 months between the groups without bouts (mean difference 13.7 min of MVPA, 95% CI: −26.8 to 54.2; p=0.51) [33].
• Findings from a prospective case series on proximal interphalangeal joint orthosis and therapeutic exercise for trigger finger demonstrate feasibility and short-term clinical improvement but cannot establish superiority over other conservative treatments due to the absence of a control group [34].
• Results from a formal 2-year cluster randomised-controlled trial confirmed the Youth-Physical Activity Towards Health programme was effective in improving youth fundamental movement skills proficiency [35].
• Brief interventions promoting physical activity in primary care and the community are likely to be inexpensive compared with usual care [37].
• A coaching intervention to enhance physical activity and prevent falls in community-dwelling people aged 60+ years improved daily steps, moderate-to-vigorous physical activity, hours per week of walking, overall well-being, quality of life and disability [38].
• Treatment groups in the WALK 2.0 trial differed significantly in trajectories of minutes/day of physical activity (p=0.0198), through a greater change at 3 months for Web 2.0 than Web 1.0 (7.3 min/day, 95% CI 2.4 to 12.3) [39].
• Compared with obesity-low physical activity, there was no survival benefit of being normal weight if physical activity levels were low [40].
• Exercise therapy is effective for some adolescents with patellofemoral pain but not all, and adherence to exercises is a challenge [41].
• Adolescents doing home exercises three times per week or more are four times more likely to be recovered after 12 months [41].
• Physical activity interventions that combine self-monitoring with other components provide an additional modest yet sustained increase in step count compared with self-monitoring alone [42].
• The PERSiST guidance attempts to address the problem of poor reporting of medical and healthcare systematic reviews in the sports and exercise medicine, musculoskeletal rehabilitation, and sports science fields [43].
• Approximately 65 min per day of walking was linked to a more favourable cardiometabolic profile [45].
• Approximately 5 min of stair climbing was linked to a more favourable cardiometabolic profile [45].
• The adverse effects of sitting became pronounced above 12 hours per day [45].
• Researchers need to prevent the '24-hour Babel' by coming to agreement about how to collectively define physical activity, sedentary behaviour and sleep through an inclusive and systematic consensus process [47].
• Exercise therapy improved health-related quality of life (SMD 0.37) in people with multimorbidity [50].
• Exercise therapy improved objectively measured physical function (SMD 0.33) in people with multimorbidity [50].
• Exercise therapy reduced depression (SMD −0.80) in people with multimorbidity [50].
• Exercise therapy reduced anxiety symptoms (SMD −0.49) in people with multimorbidity [50].

Practical Considerations

• Light-intensity physical activity is an accessible public health target and a potentially valuable complement to existing physical activity guidelines [6].
• The proportion of participants meeting the health-enhancing physical activity (HEPA) recommendations increased from 33.1% to 42.3% between baseline and first follow-up in the Allez Hop programme [12].
• Compared with control players, those who participated in the NMC programme found it to be less physically challenging but more enjoyable and potentially of more benefit [16].
• Policymakers should introduce physical activity promotion into the Quality and Outcomes Framework (QOF) as an individual indicator at a cost of approximately £1 million [24].
• Brief advice is a cost-effective way to improve physical activity among adults, provided short-term mental health gains are considered [32].

Key Evidence

• [L5] There is little evidence that physical activity is associated with significant harm, and the benefits, in general, outweigh the risks. [1] (10.1136/bjsports-2021-104634)
• [L1] Maintenance interventions may help people continue to be physically active and improve physical function and health-related quality of life. [2] (10.1136/bjsports-2025-110444)
• [L5] The 2018 US PA guidelines opened new horizons for PA and exercise medicine practice by recognising that any bouts of PA count for health. [3] (10.1136/bjsports-2018-100397)
• [Paper] ISPAH's Eight Investments That Work for Physical Activity provides a summary of eight areas for action that are supported by scientific evidence and have worldwide applicability. [4] (10.1136/bjsports-2020-103635)
• [Paper] The panel agreed on 10 major themes with strong scientific evidence that, in children and adolescents aged 6-17, participating in moderate to vigorous physical activities led to multiple positive health outcomes. [5] (10.1136/bjsports-2020-102261)
• [L5] LPA is an accessible public health target and a potentially valuable complement to existing PA guidelines, as it accounts for the majority of PA energy expenditure (51–59%). [6] (10.1136/bjsports-2025-111179)
• [L3] Sustained physical activity in older age is associated with improved overall health. [7] (10.1136/bjsports-2013-092993)
• [Paper] These 2020 WHO guidelines update previous WHO recommendations released in 2010. [9] (10.1136/bjsports-2020-102955)
• [L1] The interventions implemented at ≤12 weeks primarily improved the functional performance, whereas those lasting >12 weeks resulted in greater gains in the muscle strength and joint flexibility. [10] (10.1186/s13018-025-06430-7)
• [L1] There is moderate certainty evidence that fall prevention exercise programmes are likely to be cost-effective. [11] (10.1136/bjsports-2022-105747)
• [L4] The proportion of participants meeting the health-enhancing physical activity (HEPA) recommendations increased from 33.1% to 42.3% between baseline and first follow-up. [12] (10.1136/bjsm.2009.070201)
• [Paper] Much of the evidence presented in the statements is based on longitudinal associations from observational and randomised controlled intervention studies, as well as quantitative and qualitative social studies in relatively healthy community-dwelling older adults. [13] (10.1136/bjsports-2018-100451)
• [L1] The addition of WAT-use did not have any effect on perceived joint function or HRQoL. [14] (10.1186/s12891-024-08238-8)
• [L1] AQE appears to provide meaningful pain relief for musculoskeletal disorders, with benefits that may persist during follow-up. [15] (10.1186/s12891-026-09953-0)
• [L1] Compared with control players, those who participated in the NMC programme found it to be less physically challenging but more enjoyable and potentially of more benefit. [16] (10.1136/bjsports-2013-092816)
• [L3] About 15 times more physical activity of at least moderate intensity is needed to achieve similar results. [17] (10.1136/bjsports-2023-107252)
• [L5] RCTs have failed to provide conclusive evidence that physical activity causes a reduced risk of death. [18] (10.1136/bjsports-2017-098995)
• [L5] Moderate treadmill exercise following an initial period of short-term immobilization has a positive impact on tendon-bone interface healing, whereas prolonged immobilization has a detrimental effect on physical recovery. [19] (10.1177/2325967125s00320)
• [L1] Inverse non-linear dose–response associations suggest substantial protection against a range of chronic disease outcomes from small increases in non-occupational physical activity in inactive adults. [20] (10.1136/bjsports-2022-105669)
• [L5] The ProPASS consortium aims to bring together existing and future observational studies of thigh-worn accelerometry to produce evidence on the associations of physical activity, sitting, and sleep with long-term health outcomes and longevity. [21] (10.1136/bjsports-2019-100786)
• [Paper] The consensus statement outlines approaches that may identify determinants and modifiers of CRF exercise response and recommends future research to better understand exercise response variability. [22] (10.1136/bjsports-2018-100328)
• [L5] Acknowledging the possibility that not all daily METs are the same in our scientific inquiry is an important step towards realising the full potential of bodily movement for promoting health. [23] (10.1136/bjsports-2017-098693)
• [L5] The authors propose that policymakers should introduce physical activity promotion into the Quality and Outcomes Framework (QOF) as an individual indicator at a cost of approximately £1 million. [24] (10.1136/bjsm.2010.073726)
• [L1] PSE may act as a mechanism of action for exercise interventions, and is less successful delivered standalone. [25] (10.1186/s12891-025-09313-4)
• [L3] These findings question whether THA should be prioritized only for those patients who have severe hip OA symptoms, but require confirmation in a trial. [26] (10.1016/j.arth.2025.04.032)
• [L5] Instead, pain is modulated by many factors, and the relationship between pain and tissue becomes less predictable the longer pain persists. [27] (10.1136/bjsports-2017-098983)
• [L1] Exercise may improve pain and function with low to moderate certainty, but it is uncertain whether differences are clinically important. [29] (10.1097/corr.0000000000003476)
• [L1] Protocols using painful exercises offer a small but significant benefit over pain-free exercises in the short term, with moderate quality of evidence. [30] (10.1136/bjsports-2016-097383)
• [L1] There was a significant group-by-time interaction for mean minutes of MVPA per day in favour of the intervention group (adjusted difference between groups at follow-up=3.85 min, 95% CI (0.79 to 6.91), p≤0.01), including significantly more vigorous physical activity (2.45 min, p≤0.01), equating to 27 min more MVPA per week. [31] (10.1136/bjsports-2014-094523)
• [Paper] BA is a cost-effective way to improve PA among adults, provided short-term mental health gains are considered. [32] (10.1136/bjsports-2013-092897)
• [L1] There was no significant effect of the intervention on weekly MVPA at 12 months between the groups recorded in ≥10 min bouts (mean difference 11.8 min of MVPA, 95% CI: −2.1 to 26.0; p=0.10) or without bouts (mean difference 13.7 min of MVPA, 95% CI: −26.8 to 54.2; p=0.51). [33] (10.1136/bjsports-2020-103121)
• [L4] Because of the absence of a control group, these findings demonstrate feasibility and short-term clinical improvement but cannot establish superiority over other conservative treatments. [34] (10.1016/j.jhsg.2026.101038)
• [Paper] Results from a formal 2-year cluster randomised-controlled trial confirmed the programme was effective in improving youth FMS proficiency. [35] (10.1136/bjsports-2018-099745)
• [L1] Brief interventions promoting physical activity in primary care and the community are likely to be inexpensive compared with usual care. [37] (10.1136/bjsports-2015-094655)
• [L1] However, this programme improved other physical activity measures (ie, daily steps, MVPA, hours per week of walking), overall well-being, quality of life and disability. [38] (10.1136/bjsports-2023-107027)
• [L1] Treatment groups differed significantly in trajectories of minutes/day of physical activity (p=0.0198), through a greater change at 3 months for Web 2.0 than Web 1.0 (7.3 min/day, 95% CI 2.4 to 12.3). [39] (10.1136/bjsports-2016-096890)
• [L2] Compared with obesity-low physical activity, there was no survival benefit of being normal weight if physical activity levels were low. [40] (10.1136/bjsports-2021-104827)
• [Paper] Exercise therapy is effective for some adolescents but not all, and adherence to exercises is a challenge, with those doing home exercises three times per week or more being four times more likely to be recovered after 12 months. [41] (10.1136/bjsports-2016-096268)
• [L1] Physical activity interventions that combine self-monitoring with other components provide an additional modest yet sustained increase in step count compared with self-monitoring alone. [42] (10.1136/bjsports-2021-105198)
• [Paper] The Prisma in Exercise, Rehabilitation, Sport medicine and SporTs science (PERSiST) guidance attempts to address the problem of poor reporting of medical and healthcare systematic reviews in the sports and exercise medicine, musculoskeletal rehabilitation, and sports science fields. [43] (10.1136/bjsports-2021-103987)
• [Paper] Changes to the PA guidelines, such as removal of a 10-min bout criterion, pose challenges for PA surveillance. [44] (10.1136/bjsports-2020-102621)
• [L5] The resource also delivered the first pooled analysis exploring physical activity type in relation to cardiometabolic health, showing that approximately 65 min per day of walking and 5 min of stair climbing were each linked to a more favourable cardiometabolic profile, while the adverse effects of sitting became pronounced above 12 hours per day. [45] (10.1136/bjsports-2025-111283)
• [Paper] At follow-up, 65.0% of inactive participants were taking part in sport and 85.6% were meeting recommended MVPA guidelines. [46] (10.1136/bjsports-2017-097716)
• [L5] Researchers need to prevent this looming ‘24-hour Babel’ by coming to agreement about how to collectively define PA, SB and sleep through an inclusive and systematic consensus process. [47] (10.1136/bjsports-2021-104487)
• [L1] However, most of these differences did not reach the minimum threshold to be considered clinically important. [48] (10.1016/j.jht.2024.07.006)
• [L2] Similarly, individuals not achieving the WHO guideline for physical activity showed an elevated risk, even if they were abdominally lean (HR 1.04, 95% CI 1.01 to 1.07). [49] (10.1136/bjsports-2024-108708)
• [L1] Exercise therapy improved health-related quality of life (SMD 0.37) and objectively measured physical function (SMD 0.33) and reduced depression (SMD −0.80) and anxiety symptoms (SMD −0.49). [50] (10.1136/bjsports-2021-104367)

References

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[18] Physical activity and longevity: how to move closer to causal inference. British Journal of Sports Medicine. 2018. DOI: 10.1136/bjsports-2017-098995

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[50] Infographic. Benefits and harms of exercise therapy in people with multimorbidity. British Journal of Sports Medicine. 2021. DOI: 10.1136/bjsports-2021-104367