De Quervain's Tenosynovitis Impormasyon In-depth

Ang pahinang ito ay isinalin ng makina at hindi pa nasusuri ng isang doktor. Ang bersyong Ingles ang siyang opisyal.

Ang iyong nararamdaman

Ang De Quervain's tenosynovitis ay nagdudulot ng sakit sa bahagi ng iyong pulso na malapit sa hinlalaki, malapit sa base ng hinlalaki. Ang bahaging ito ay maaari ring maging sensitibo sa hipo at bahagyang namamagâ. Ang problema ay nasa isang makitid na tunnel kung saan dumadaan ang dalawang tendon ng hinlalaki, at kapag ang tunnel na iyon ay naiirita, sumasabit ang mga tendon habang gumagalaw.

May mga partikular na paggalaw na nagpapalala sa sakit. Ang pagbaluktot ng iyong pulso patungo sa panig ng kalingkingan, ang mahigpit na paghawak habang ibinabaluktot ang pulso, o ang pag-ipit ng iyong hinlalaki at hintuturo ay maaaring mag-trigger nito. Maaari mo itong mapansin kapag nagbubuhat ng kettle, nagpihit ng door handle, bumuhat ng iyong sanggol, o gumagamit ng gunting. Para sa ilang tao, ang sakit ay sumisidhi pagkagising o pagkatapos ng isang serye ng aktibidad.

Ang sanhi ay hindi malinaw na nauugnay sa iyong trabaho o sa isang partikular na pinsala. Maaari itong lumitaw kasabay ng iba pang problema sa pulso, ngunit madalas itong nabubuo nang mag-isa.

Kadalasan ay nadi-diagnose ito ng iyong surgeon sa pamamagitan ng pagsusuri sa iyong pulso at pagtukoy kung nasaan ang sakit. Hindi kinakailangan ang mga scan kapag malinaw na ang sitwasyon. Ginagamit lamang ang imaging kung may iba pang dapat suriin, gaya ng lumang bali sa pulso o arthritis sa base ng hinlalaki.

Karamihan sa mga tao ay nagsisimula muna sa simpleng gamutan, at karamihan ay nakikita na ang kanilang mga sintomas ay humuhupa sa loob ng isang taon. Ang steroid injection sa sensitibong tunnel ang karaniwang unang hakbang, at gumagana ito sa loob ng dalawang injection para sa 73.4% ng mga tao. Ang paggamit ng splint lamang ay hindi gaanong epektibo kaysa sa injection.

Kung ang iyong sakit ay malala, o pinipigilan ka nito sa paggawa ng mga bagay na kailangan mong gawin, maaaring talakayin ang operasyon upang paluwagin ang masikip na tunnel. Tinatawag itong release of the first extensor compartment, at ito ang standard na gamutan kapag ang mga injection ay hindi sapat na nakatulong.

Ano ang aktwal na nangyayari

Ang dalawang tendon na nagpapagalaw sa iyong hinlalaki palabas at palayo sa iyong kamay ay dumadaan sa isang makitid na tunnel sa bahagi ng hinlalaki ng iyong pulso. Isipin ang mga tendon bilang mga makinis na kable at ang tunnel bilang isang pulley strap na humahawak sa mga ito nang malapit sa buto. Sa kondisyong ito, ang tunnel ay nagiging masikip at makapal, kaya nawawala ang madaling pagdausdos ng mga kable.

Ang friction sa pagitan ng tendon at tunnel ay nagdudulot ng pamamaga sa loob ng espasyong iyon. Sa paglipas ng panahon, ang tendon sheath mismo ay nagbabago: ito ay nagiging dense at fibrous, at ang tissue ay nagkakaroon ng katangiang parang gel. Ang mga tendon ay maaari ring magkaroon ng mga sticky band na nagdidikit sa mga ito sa dingding ng tunnel. Ang resulta ay isang masikip at makitid na channel, at bawat galaw ng hinlalaki ay humihila sa mga namamagang kable sa loob nito. Ang paghila na iyon ay nairirita ang mga pain sensor sa strap, kaya naman masakit ang mga pinch at grip movement na nabasa mo sa itaas.

Ang tunnel ay maaari ring likas na makitid sa ilang tao. Isang extra wall sa loob nito, na humahati sa espasyo sa dalawang compartment, ay naroroon sa halos isang katlo ng populasyon, at ang ilang tao ay may mga extra tendon slip na nagsasalo sa parehong masikip na espasyo. Ang mga baryasyong ito ay matatagpuan sa parehong pulso ng ilang tao, at ginagawa nitong mas malamang ang pagsisikip.

Ang kondisyong ito ay madalas tawaging tenosynovitis, na tunog pamamaga ng lining ng tendon. Sa katunayan, ang mga pagbabago sa tissue ay mas malapit sa pagkapudpod (wear) at degeneration kaysa sa klasikong pamamaga (inflammation). Ang pamamaga at pagkapal ay totoo, ngunit nagmumula ang mga ito sa pagkasira ng tendon sheath sa ilalim ng load sa halip na mula sa isang simpleng flare ng inflammation.

Ang sakit ay hindi tanda na napinsala mo ang iyong pulso dahil sa overuse. Walang malinaw na link na naitatag sa pagitan ng paggamit ng kamay sa trabaho o isang partikular na pinsala at sa kondisyong ito. Mas karaniwan ito sa mga kababaihan, at maaari itong lumitaw pagkatapos ng iba pang mga problema sa pulso gaya ng wrist fracture na ginamot sa pamamagitan ng operasyon.

Ano ang maaari naming gawin tungkol dito

Si Dr Kieran Hirpara, isang upper-limb surgeon sa Mater Private Hospital Rockhampton, ay nagsisimula sa mga opsyon na hindi gaanong invasive na angkop sa iyong kondisyon. Ang mga pasyente ay karaniwang nirerefer sa aming klinika ng kanilang GP; kung iminungkahi ng isang physiotherapist na magpatingin sa amin, kakailanganin mo pa rin ng referral mula sa iyong GP upang maging eligible para sa Medicare rebate. Sa iyong unang pagbisita, kukuha kami ng history, susuriin ang iyong pulso (wrist) at mag-aayos ng imaging kung may kailangan pang suriin. Dahil ang problemang ito ay matagal na at hindi isang bagong pinsala, karaniwan kaming nagsisimula sa non-operative care.

Ang mga unang hakbang ay mga bagay na maaari mong gawin nang mag-isa. Nakakatulong ang pagpapahinga ng hinlalaki at pulso, at ang isang thumb spica splint ay pinapanatiling hindi gumagalaw ang hinlalaki at pulso upang makapagpahinga ang naiiritang tunnel. Ang splint ay maaaring magpakalma ng sakit habang suot ito, ngunit hindi ito patuloy na gumagana kapag malaya nang gumagalaw ang mga joint. Ang hand therapy ay maaaring idagdag sa isang injection, at ang kombinasyong ito ay napatunayang nakakabawas ng sakit sa pagsusuri [2]. Mayroon ding mga treatment kung saan ang isang medicated cream ay itinutulak sa balat sa pamamagitan ng maliit na electric current, o kung saan ang sound waves ay ipinupulse sa masakit na bahagi; ang mga ito ay maaaring magpahusay sa paggana ng pulso at magpagaan ng sakit.

Ang pangunahing medical treatment ay isang cortisone injection sa loob ng tunnel. Ang cortisone ay isang malakas na anti-inflammatory medicine na nagpapakalma ng pamamaga sa paligid ng mga tendon. Ang isang injection ay nag-alis ng mga sintomas sa 82% ng mga pasyente, at higit sa kalahati sa mga ito ay nanatiling walang sintomas sa loob ng hindi bababa sa 12 buwan. Kung ikaw ay may diabetes, mas mababa ang posibilidad na gumana ang isang injection para sa iyo, ngunit ang mga paulit-ulit na injection ay hindi nawawala ang bisa. Ang pagsasama ng injection at splint ay mas epektibo kaysa sa injection lamang. Ang ibang mga injection, gaya ng hyaluronic acid o PRP, ay hindi bahagi ng treatment na inaalok namin para sa kondisyong ito.

Kung ang non-operative care ay hindi nagbigay sa iyo ng sapat na ginhawa, pag-uusapan natin ang surgery. Ang operasyon ay nagpapaluwag sa masikip na tunnel upang ang mga tendon ay muling makagalaw nang malaya, at ito ay isinasaalang-alang kapag ang mga injection at splinting ay hindi nakapagpakalma ng iyong mga sintomas. Tatalakayin namin kung ano ang kinapapalooban ng operasyon, kung ano ang hitsura ng recovery at kung ano ang mga resulta bago ka magdesisyon kasama namin.

Ano ang dapat asahan

Para sa karamihan ng mga tao, gumagaling ang kondisyong ito sa paglipas ng panahon. Karamihan sa mga pasyente ay nakikita na nawawala ang kanilang mga sintomas sa loob ng isang taon. Maraming tao ang nakakapag-manage nang maayos nang walang operasyon: mga isang katlo lamang ng mga taong may kondisyong ito ang nauuwi sa pangangailangan ng operasyon sa loob ng dalawang taon, at kapag kailangan ang operasyon, karaniwan itong nangyayari sa loob ng unang taon.

Layunin ng gamutan na paikliin ang prosesong iyon. Ang cortisone injection kasama ang maikling panahon ng paggamit ng splint ang pangunahing paraan ng maagang pangangalaga, at gumagana ito para sa karamihan ng mga tao. Kung nakatulong ang unang injection ngunit bumalik ang sakit, ang pangalawang injection ay isa pa ring makatwirang opsyon. Bumababa ang success rate sa mga paulit-ulit na injection, ngunit nananatili itong isang kapaki-pakinabang na tool.

Kung ikaw ay may diabetes, ang isang injection ay mas maliit ang posibilidad na magpagaling ng iyong mga sintomas kumpara sa ibang mga tao. Ang mabuting balita ay ang mga susunod na injection ay hindi nawawalan ng bisa sa mga taong may diabetes, kaya ang pag-uulit ng gamutan ay nananatiling kapaki-pakinabang.

Ang operasyon ay nakalaan para sa mas maliit na grupo na ang sakit ay hindi gumagaling sa pamamagitan ng mga injection at splinting. Kapag nangyari iyon, ang pag-release sa masikip na tunnel ay nagbibigay ng pangmatagalang ginhawa para sa mga tendon, at ang operasyon ay may mababang rate ng mga komplikasyon.

Mahalaga rin kung paano mo iniisip ang kondisyon. Ang mga taong nag-eexpect ng pinakamasamang mangyayari ay may tendensiyang mag-ulat ng mas maraming sakit at mas mababang function, kaya ang isang malinaw na larawan ng kung ano ang naghihintay ay makakatulong sa iyo na piliin ang gamutan na angkop sa iyong buhay. Ang pag-aalala na napinsala mo ang iyong wrist dahil sa overuse ay hindi suportado ng ebidensya, at ang pagkaalam nito ay maaaring mag-alis ng ilang takot sa mga flare-up.

Walang iisang garantisadong timeline. Ang ilang mga wrist ay mabilis na tumutugon sa isang injection, ang iba ay nangangailangan ng repeat dose, at ang ilan ay nauuwi sa operasyon. Ang karaniwang nangyayari kapag ang kondisyong ito ay na-manage nang maayos ay nababawasan ang sakit at muling malayang nakaka-glide ang mga tendon. Kung hahayaan lamang, karamihan sa mga kaso ay gumagaling pa rin sa loob ng isang taon, ngunit maaari kang gumugol ng maraming buwan sa pag-manage ng discomfort habang naghihintay.

Kailan dapat magpatingin

Magpatingin sa iyong GP kung ang sakit sa bahagi ng thumb side ng iyong wrist ay pabalik-balik, o kung pinipigilan nito ang paggawa ng iyong mga karaniwang gawain sa kabila ng pahinga at paggamit ng splint. Humingi ng specialist review kung ang mga injection ay hindi nakapagpagaling, o kung ang sakit ay sapat na malala upang limitahan ang paggamit mo ng iyong kamay sa araw-araw. May ilang tao na napapansin na ang kanilang mga sintomas ay nababawasan sa loob ng isang taon nang kusa, ngunit ang paghihintay ay hindi lamang ang tanging opsyon, at ang paggamot ay maaaring magpaikli sa panahong iyon. Kung mapansin mo ang bagong pamamanhid, pangingilig, o mga hindi pangkaraniwang sensasyon sa thumb o wrist na hindi tumutugma sa karaniwang pattern, banggitin ito sa iyong appointment, dahil ang ibang mga problema sa wrist ay maaari ring magmukhang ganitong kondisyon.

Mas malalim na pagtalakay

Advanced reading: the deeper science (optional)

Ang seksyong ito ay higit pa sa kailangan mo para sa iyong sariling mga desisyon sa paggamot. Ang De Quervain's tenosynovitis ay karapat-dapat sa karagdagang pagbabasa dahil sa isang maliit na anatomical variant na sanhi ng malaking bahagi ng kawalan ng kasiyahan pagkatapos ng isang operasyon na sa madaling salita ay maaasahan, at dahil ang pinakamahusay na non-operative na resulta ay nagmumula sa pagsasama ng dalawang paggamot sa halip na pumili sa pagitan nila.

Mas mahusay ang kombinasyon kaysa sa alinman sa mga bahagi nito

Ang unang dorsal compartment ay naglalaman ng dalawang tendon sa isang tunnel sa bahagi ng thumb ng wrist. Layunin ng gamutan na pawiin ang pamamaga sa tunnel na iyon at bawasan ang load na dumadaan dito.

Isang network meta-analysis ng 823 na pasyente ang nagkonkludo na ang corticosteroid injection na may maikling tagal ng immobilisation ay nananatiling primary at epektibong gamutan, habang ang extracorporeal shockwave therapy ay isang secondary na opsyon [1]. Sa direktang pagsusuri sa mga bahagi nito, ang mga pinagsamang approach ng orthosis at corticosteroid injection ay mas epektibo kaysa sa alinman sa mga interbensyong ito nang mag-isa [2].

Ito ay isang mas espesipikong instruksyon kaysa sa "subukan ang splint, pagkatapos ay injection kung mabigo ito". Sinusuportahan ng ebidensya ang paggawa ng dalawa nang magkasama, kung saan ang splint ay isusuot sa isang itinakdang maikling panahon pagkatapos ng injection.

Sulit pa rin ang pangalawang injection

Kapag bumalik ang mga sintomas, ang reflex ay magkonklusyon na nabigo ang mga injection at lumipat na sa operasyon. Ang data mula sa isang malaking cohort ay nagsasabing hindi ito totoo: bagaman ang success rate ay bumababa sa maraming injection, ang mga repeat injection ay may mataas na rate ng tagumpay at isang viable na clinical option [3].

Inaasahan ang pagbaba ng tagumpay sa pag-uulit. Ngunit ang mas mababang success rate ay hindi katulad ng kawalan ng saysay, at ang pangalawang injection ay nananatiling isang makatwirang hakbang sa halip na isang taktika lamang sa pagpapaliban.

Ang variant na nagpapaliwanag sa karamihan ng surgical disappointment

Ang release ng first dorsal compartment ay epektibo, at kung saan ito nabibigo ay karaniwang may isang partikular na dahilan. Ang kawalan ng kasiyahan ay maaaring magresulta mula sa incomplete release, tendon subluxation, nerve injury, o simpleng tagal ng recovery, at ang isang hindi natukoy at hindi na-release na extensor pollicis brevis subsheath ay isang discrete na pinagmumulan ng kawalan ng kasiyahan [4].

Nararapat itong himayin dahil ito ang pinaka-kapaki-pakinabang na katotohanan sa seksyong ito. Sa isang malaking proporsyon ng mga tao, ang compartment ay hindi isang tunnel kundi dalawa, kung saan ang extensor pollicis brevis tendon ay tumatakbo sa sarili nitong hiwalay na sheath sa tabi ng isa pa. Ang isang release na nagbubukas sa pangunahing compartment at humihinto ay nag-iiwan sa ikalawang sheath na intact, at ang tendon sa loob nito ay compressed pa rin. Ang wrist ay binuksan, ang operasyon ay nakumpleto gaya ng inilarawan, at ang mga sintomas ay nananatili.

Ito rin ang dahilan kung bakit mahalaga ang dalawa pang nakalistang sanhi: ang pag-release nang masyadong malawak ay nagpapahintulot sa mga tendon na mag-subluxate palabas ng groove kasabay ng paggalaw ng wrist, na nagdudulot ng isang masakit na snap, at ang superficial branch ng radial nerve ay tumatawid agad sa operative field. Ang compartment ay dapat buksan nang kumpleto ngunit hindi labis, habang may nerve sa daan, kung kaya't ang isang tila maliit na operasyon ay nangangailangan ng parehong pag-iingat gaya ng isang mas malaking operasyon.

Hindi lahat ng nasa radial wrist ay de Quervain's

Ang pananakit sa rehiyong ito ay may differential na dapat malaman, dahil magkakaiba ang mga gamutan: arthritis sa base ng thumb, intersection syndrome ilang sentimetro ang layo pataas sa forearm, at radial nerve irritation ay maaari lahat magdulot ng pananakit sa magkakapatong na teritoryo. Ang localised tenderness nang direkta sa ibabaw ng compartment, kung saan ang pananakit ay nauulit sa pamamagitan ng ulnar deviation ng wrist habang ang thumb ay nakatupi sa palad, ang nagtuturo sa tendon sheath sa halip na sa mga katabi nito.

Mga Sanggunian

[1] Chong HH, Pradhan A, Dhingra M, Liong W, Hau MY, Shah R. Advancements in de Quervain tenosynovitis management: a comprehensive network meta-analysis of randomized controlled trials. J Hand Surg Am. 2024;49(6):557-69. https://doi.org/10.1016/j.jhsa.2024.03.003

[2] Cavaleri R, Schabrun SM, Te M, Chipchase LS. Hand therapy versus corticosteroid injections in the treatment of de Quervain's disease: a systematic review and meta-analysis. J Hand Ther. 2016;29(1):3-11. https://doi.org/10.1016/j.jht.2015.10.004

[3] Hassan K, Sohn A, Shi L, Lee M, Wolf JM. De Quervain tenosynovitis: an evaluation of the epidemiology and utility of multiple injections using a national database. J Hand Surg Am. 2022;47(3):284.e1-284.e6. https://doi.org/10.1016/j.jhsa.2021.04.018

[4] Rogozinski B, Lourie GM. Dissatisfaction after first dorsal compartment release for de Quervain tendinopathy. J Hand Surg Am. 2016;41(1):117-9. https://doi.org/10.1016/j.jhsa.2015.09.003


Evidence & references

This is the clinical evidence summary written for health professionals. It is technical, and it lists the research this page was built from. You do not need to read it to understand your treatment or to make a decision about it.

Overview

Anatomy

  • Anatomical variations in the first extensor compartment are clinically relevant to the pathophysiology and treatment of De Quervain's tenosynovitis [1].

Non-Operative Management

  • Corticosteroid injection is the only available nonsurgical treatment that can potentially modify the course of de Quervain's tenosynovitis [2].
  • Corticosteroid injection with a short duration of immobilization is the primary and effective treatment for de Quervain tenosynovitis [14].
  • The success rate for treating De Quervain's tenosynovitis decreases with multiple injections [25].
  • Repeat injections for De Quervain's tenosynovitis have a high rate of success and are a viable clinical option [25].
  • Patients presenting with de Quervain's tenosynovitis may favor initial nonsurgical management [8].

Operative Management

  • Surgical release of De Quervain's tenosynovitis remains the gold standard treatment [6].
  • Longitudinal incision for surgical release offers the advantage of easy identification of the compartment [6].
  • Longitudinal incision for surgical release offers the advantage of more complete releases of tendon sheath and peritendinous adhesions [6].
  • Longitudinal incision for surgical release offers the advantage of less risk of palmar subluxation of tendons [6].
  • Release of the first extensor compartment for refractory de Quervain's disease results in good clinical outcomes with minimal morbidity [12].
  • Endoscopic release of the extensor compartment is an effective and safe procedure for patients with de Quervain's disease who are unresponsive to nonoperative treatments [28].
  • Endoscopic release of the extensor compartment is associated with a slight increase in operation time compared to open release [28].
  • Endoscopic release for de Quervain's tenosynovitis provides earlier improvement after surgery compared with open release [30].
  • Endoscopic release for de Quervain's tenosynovitis is associated with fewer superficial radial nerve complications compared with open release [30].
  • Endoscopic release for de Quervain's tenosynovitis is associated with greater scar satisfaction compared with open release [30].
  • Pulley reconstruction should be considered part of the surgical treatment for de Quervain tenosynovitis [4].
  • Pulley reconstruction for de Quervain tenosynovitis provides satisfactory medium-term results [4].

Patient Factors and Outcomes

  • Patients who scored lower than 40 for physical function had significantly increased odds of eventually undergoing surgical release for de Quervain tenosynovitis [23].
  • Patients who scored higher than 60 for pain interference had significantly increased odds of eventually undergoing surgical release for de Quervain tenosynovitis [23].
  • Addressing misconceptions about the consequences of de Quervain's tenosynovitis and symptom duration allows patients to make informed decisions about treatment [5].

Anatomy & Pathophysiology

Anatomical Variations

  • The EPB tendon is the most dorsal tendon in the first dorsal compartment and can be identified by its distally oriented muscle fibers [15].
  • The APL tendon has no muscular fibers in the area of the first dorsal compartment [15].
  • Separate compartments for the EPB and APL tendons are occasionally found, requiring identification of a septum [15].
  • If the EPB tendon is absent, the floor of the compartment may show a Y-shaped tendinous insertion of the brachioradialis tendon [15].
  • The superficial branch of the radial nerve is expected to be encountered in more than 50% of patients undergoing surgery for De Quervain's tenosynovitis [58].
  • The radial artery courses dorsally just beyond the radial styloid, requiring caution during septum resection [15].

Pathological Mechanisms

  • De Quervain's syndrome is defined as inflammation of the APL and EPB tendons in the first dorsal compartment caused by friction within a tight osteoligamentous tunnel [3].
  • Friction between the APL and EPB tendons leads to compromised blood flow and nutrition, resulting in adhesion development and tendon stenosis [3].
  • De Quervain's syndrome may involve myxoid degeneration, a process where connective tissues are replaced by a gelatinous or mucoid substance [3].
  • De Quervain's syndrome is associated with trauma, extensor carpi ulnaris involvement, ligament instability, and repetitive strain [3].
  • Tenovaginitis in the first extensor compartment is characterized by thickening of the fibrous sheath [11].
  • De Quervain's disease results from anatomical factors associated with mechanical stressors [43].
  • Women are more affected by De Quervain's disease than men due to manual work influencing first compartment dynamics [43].
  • Training intensity is a major factor in determining De Quervain's disease in volleyball players [43].
  • Wrist position influences the excursion of the extensor pollicis brevis tendon [44].
  • Stenosing tenosynovitis causes a significant decrease in maximum velocity during slow fist tasks [48].

Classification

Anatomical Variations and Pathophysiology

  • De Quervain's syndrome is defined as a condition originating when the abductor pollicis longus (APL) and extensor pollicis brevis (EPB) tendons in the first dorsal compartment become inflamed through friction within a tight osteoligamentous tunnel [3].
  • The condition is characterized by compromised blood flow and nutrition, leading to adhesions and tendon stenosis [3].
  • De Quervain's syndrome may represent a myxoid degeneration, defined as a degenerative process where connective tissues are replaced by a gelatinous or mucoid substance [3].
  • Terminology for the condition varies, including tendinosis (degeneration without inflammation), tendinopathy (injury to the tendon), and tenosynovitis (inflammation or thickening of the fibrous sheath wall) [3].
  • De Quervain's syndrome may not be an isolated pathology and has been associated with trauma, extensor carpi ulnaris involvement, ligament instability, and repetitive strain [3].
  • The prevalence of a septated first dorsal compartment is considerably higher in patients with De Quervain tenosynovitis than previously reported [42].
  • An intracompartmental septum between the APL and EPB tendons is present in a mean of 43% of wrists in cadaveric studies, with a range of 20% to 75% [17].
  • The presence of an intracompartmental septum detected by ultrasound is associated with the failure of ultrasound-guided steroid injection [17].
  • In a prospective study, 22 of 30 wrists (73%) that failed nonsurgical treatment and underwent operative release were found to have a separate compartment for the extensor pollicis brevis [32].
  • The prevalence of a separate extensor pollicis brevis compartment in patients failing nonsurgical treatment is significantly higher than in the general population [32].
  • In cases where constriction involves only the extensor pollicis brevis in a separate compartment, exploration of both compartments is advised [18].
  • Radial styloid abnormalities do not affect the outcome of management for de Quervain's disease [10].

Epidemiology and Risk Factors

  • The unadjusted incidence rate of de Quervain's tenosynovitis in a young, active population was 0.94 per 1000 person-years [31].
  • The unadjusted incidence rate for female patients was 2.81 per 1000 person-years, compared with 0.62 per 1000 person-years for male patients [31].
  • The adjusted incidence rate ratio for females, with males as the referent category, was 4.45 (95% CI 4.28, 4.62) [31].
  • The highest incidence rate was observed in the ≥40-year-old group at 1.37 per 1000 person-years [31].
  • The adjusted incidence rate ratio for the ≥40-year-old group, compared to the <20-year-old group, was 3.65 (95% CI 3.26, 4.09) [31].
  • Non-white race is a risk factor for de Quervain's tenosynovitis, with an adjusted incidence rate ratio of 1.31 (95% CI 1.21, 1.42) for black race and 1.17 (95% CI 1.05, 1.25) for other races compared to white race [31].
  • De Quervain's syndrome affects approximately 1.3% of women and 0.5% of men in a population of adults of working age [17].

Diagnostic and Clinical Considerations

  • Routine wrist radiography prior to surgeon evaluation is wasteful as patients do not benefit from the resulting radiologic data [7].
  • Addressing misconceptions about the consequences of de Quervain's tenosynovitis and symptom duration allows patients to make informed treatment decisions [5].
  • Patients with a physical function score lower than 40 or a pain interference score higher than 60 on PROMIS measures had significantly increased odds of undergoing surgical release [23].

Clinical Presentation

Anatomy and Pathophysiology

  • De Quervain's syndrome is defined as a condition where the abductor pollicis longus (APL) and extensor pollicis brevis (EPB) tendons in the first dorsal compartment become inflamed through friction, leading to pain [3].
  • In De Quervain's syndrome, blood flow and nutrition become compromised, causing adhesions that lead to tendon stenosis [3].
  • The condition is referred to by various terminologies including tendinosis, tendinopathy, and tenovaginitis/tenosynovitis [3].
  • Fritz de Quervain described pain over the first dorsal compartment as a tenosynovitis following repetitive activity in 1895 [3].
  • Theodor Kocher described de Quervain's as a "fibrous tendovaginitis" around the same time, noting that his patients lacked a history of repetitive strain [3].
  • The pain in de Quervain's disease is attributed to friction of the EPL and APB against the pulley of zone 7 of the first extensor compartment [35].
  • This friction results in initial tendinopathy followed by reactive thickening of the pulley [35].
  • A septum can be present between the EPB and APL tendons within the first dorsal compartment [35].
  • The EPB tendon is very small in bulk, while the APL has a variable number of tendons in its final portion at insertion [35].
  • De Quervain's syndrome may not be an isolated pathology and may be associated with trauma, extensor carpi ulnaris involvement, ligament instability, or repetitive strain [3].

Clinical Symptoms and Signs

  • Patients with de Quervain's tenosynovitis mostly complain of soreness and tenderness on the radial side of the distal radius [35].
  • Symptoms are exacerbated by ulnar deviation of the thumb [35].
  • Symptoms are exacerbated by a strong grasp combined with flexion and radial deviation of the wrist [35].
  • Symptoms are exacerbated by firm pinching together of the index finger and thumb [35].
  • Physical examination reveals tenderness and swelling directly over the first dorsal compartment [35].
  • Palpation findings include feeling for moving nodularity, tendon rub, or popping directly over the tendon [38].

Diagnostic Testing

  • Finkelstein's test is described as the standard test to confirm the diagnosis of de Quervain's tenovaginitis [35].
  • The WHAT test (wrist hyperflexion and abduction of the thumb) is a more specific and sensitive test to diagnose de Quervain tenosynovitis than Eichhoff’s Test [35].
  • Finkelstein's test is superior to Eichhoff's test in the investigation of de Quervain's disease [38].
  • The clinical diagnosis of de Quervain's tenosynovitis involves pain and tenderness over the radial styloid and either pain at the radial styloid reproduced by resisted thumb extension or a positive Finkelstein's test result [26].
  • Using the asymptomatic thumb as a standard measure to identify the symptomatic thumb's impairments associated with de Quervain's disease may be invalid [39].

Imaging

  • Plain radiographic findings do not routinely predict the need for surgery or alter treatment courses in the initial diagnosis of De Quervain's tenosynovitis [37].
  • In a study of 200 patients, 69.1% had at least one positive radiographic finding, with carpometacartic joint arthritis being the most common finding seen in 30.9% of cases [37].
  • No radiographic findings altered the course of treatment in patients with isolated De Quervain's tenosynovitis [37].

Patient Factors and Perception

  • More negative perceptions of the consequences of de Quervain's tenosynovitis are associated with worse pain and reduced function at baseline in patients awaiting surgical decompression [21].
  • Worse pain catastrophizing is associated with worse pain and reduced function at baseline in patients awaiting surgical decompression of de Quervain's tenosynovitis [21].

Investigations

Imaging

  • Ultrasound is a useful imaging technique for diagnosing de Quervain's disease and provides important information about anatomic variations within the first extensor compartment [40].
  • Ultrasound is a worthwhile preoperative investigation in case of de Quervain's disease [41].
  • Styloid abnormalities do not affect the outcome of management for de Quervain's disease [10].

Anatomical Variations

  • Anatomic variations in the first extensor compartment are clinically relevant in the pathophysiology and treatment of De Quervain's tenosynovitis [1].
  • The presence of a septum does not significantly affect clinical outcomes or complications following endoscopic release for de Quervain's syndrome [20].
  • When the extensor pollicis brevis tendon is associated with thumb interphalangeal joint extension, it is likely to reside in a subcompartment of the first dorsal compartment, particularly in patients with de Quervain's disease [46].

Treatment

Non-Operative

  • Injection of corticosteroids is the only available nonsurgical treatment that can potentially modify the course of de Quervain's tenosynovitis and is the preferred initial treatment [2].
  • One or two local injections of 1 ml triamcinolonacetonide 10 mg/ml provided by general practitioners lead to short-term improvement in participants with de Quervain's tenosynovitis compared to placebo [19].
  • Corticosteroid injections are a useful treatment for de Quervain's tenosynovitis, leading to treatment success 73.4% of the time within 2 injections [13].
  • Pain and clinical outcomes significantly improved after corticosteroid injection in de Quervain's disease [29].
  • Although the success rate for the treatment of De Quervain's tenosynovitis decreases with multiple injections, repeat injections have a high rate of success and are a viable clinical option [25].
  • Patients with diabetes mellitus have a decreased probability of success following a single corticosteroid injection for de Quervain tenosynovitis in comparison to nondiabetic patients [27].
  • The effectiveness of each additional corticosteroid injection does not appear to diminish in patients with diabetes mellitus [27].
  • The presence of an intracompartmental septum detected by ultrasound is associated with the failure of ultrasound-guided steroid injection in de Quervain’s syndrome [17].
  • Providers should remain cognizant that patients presenting with de Quervain's tenosynovitis may favor initial nonsurgical management [8].
  • Addressing misconceptions about de Quervain's tenosynovitis in terms of the consequences for patients and how long their symptoms will last should allow patients to make informed decisions about the treatment that best matches their values [5].
  • The practice of obtaining routine wrist radiography prior to surgeon evaluation is wasteful as patients do not benefit from the resulting radiologic data [7].

Operative

  • Longitudinal incision offers the advantage of easy identification of the compartment, more complete releases of tendon sheath and peritendinous adhesions, and less risk of palmar subluxation of tendons [6].
  • The release of the first extensor compartment for refractory de Quervain's disease resulted in good clinical outcomes with minimal morbidity [12].
  • Endoscopic release of the extensor compartment is an effective and safe procedure in patients with de Quervain's disease who are unresponsive to nonoperative treatments [28].
  • Endoscopic release of the first extensor compartment is associated with a slight increase in operation time compared to open release [28].
  • Pulley reconstruction should be considered part of the surgical treatment for de Quervain tenosynovitis and gives satisfactory medium-term results [4].
  • Anatomic variations are frequently encountered in recalcitrant cases of de Quervain tenosynovitis [50].
  • Examples of anatomic variations encountered in recalcitrant cases include multiple slips of the abductor pollicis longus and the extensor pollicis brevis in its own separate compartment [50].
  • Outcomes for surgical treatment of de Quervain tenosynovitis are generally excellent [50].
  • Complications of surgical treatment for de Quervain tenosynovitis include iatrogenic injury to the superficial branch of the radial nerve, tendon subluxation, complex regional pain syndrome, and recurrence due to incomplete release [50].
  • The dorsal retinaculum is released during surgical treatment to prevent volar tendon subluxation [50].
  • Surgical decompression should be considered if corticosteroid injection fails [17].
  • The volarly based retinacular flap must remain over the released tendons to prevent volar tendon subluxation during surgical release [15].
  • The first dorsal compartment is opened on its dorsoulnar side during surgical release [15].
  • If the abductor pollicis longus and extensor pollicis brevis tendons cannot be easily retracted from the radial styloid, the surgeon should look for additional “aberrant” tendons and separate compartments [15].
  • Releasing the extensor pollicis brevis tendon first and then the abductor pollicis longus usually reveals the presence or absence of a septum [15].
  • If there is no extensor pollicis brevis present, the surgeon should inspect the floor of the compartment for the footprint of the brachioradialis tendon [15].
  • The brachioradialis tendon has a Y-shaped tendinous insertion, and if this is clearly seen, release of this compartment is assured [15].
  • Resection of a pronounced septum is warranted during surgical release, ensuring not to injure the underlying radial artery coursing dorsally just beyond the radial styloid [15].

Complications

Anatomical Variations and Surgical Risks

  • The longitudinal incision technique creates a longer area in which skin scar may make cutaneous nerves more subject to scar adherence [15].
  • The radial artery courses dorsally just beyond the radial styloid and must be avoided during septum resection [15].
  • The volarly based retinacular flap must remain over the released tendons to prevent volar tendon subluxation [15].
  • A longitudinal incision offers a less risk of palmar subluxation of tendons compared to other approaches [6].

Diagnostic and Anatomical Complications

  • Finkelstein's test is a descriptive error that can produce a false positive [9].
  • Extensor pollicis longus tenosynovitis can mimic de Quervain's disease because of its course through the first extensor compartment [9].
  • The prevalence of a separate compartment for the extensor pollicis brevis is significantly higher in patients with unsatisfactory non-operative outcomes than in the general population [32].
  • An intracompartmental septum is present in a mean 43% of wrists in cadaveric studies, with a range of 20 to 75% across different series [17].
  • Patients with diabetes mellitus have a decreased probability of success following a single corticosteroid injection for de Quervain tenosynovitis compared to nondiabetic patients [27].

Recovery

Non-Operative

  • Corticosteroid injection with a short duration of immobilization remains the primary and effective treatment for de Quervain tenosynovitis [14].
  • According to the limited evidence available, injection of corticosteroids is the only available nonsurgical treatment that can potentially modify the course of de Quervain's tenosynovitis and is therefore the preferred initial treatment [2].
  • Corticosteroid injections lead to treatment success 73.4% of the time within 2 injections [13].
  • Most informed patients initially elect symptomatic treatment for de Quervain's disease, and most experience symptom resolution within one year [33].

Operative

  • Endoscopic release for de Quervain's tenosynovitis seems to provide earlier improvement after surgery, with fewer superficial radial nerve complications and greater scar satisfaction, when compared with open release [30].
  • Pulley reconstruction should be considered part of the surgical treatment for de Quervain tenosynovitis, as the technique gives satisfactory medium-term results [4].

Patient Factors and Prognosis

  • Patients who scored lower than 40 for physical function or higher than 60 for pain interference had significantly increased odds of eventually undergoing surgical release for de Quervain tenosynovitis [23].
  • More negative perceptions of the consequences of de Quervain's tenosynovitis and worse pain catastrophizing are associated with worse pain and reduced function at baseline in patients awaiting surgical decompression [21].

Key Evidence

  • [L4] These variations are clinically relevant in the pathophysiology and treatment of De Quervain's tenosynovitis. [1] (10.1016/j.bjps.2016.08.020)
  • [L4] According to the limited evidence available, injection of corticosteroids is the only available nonsurgical treatment that can potentially modify the course of de Quervain's tenosynovitis and is therefore the preferred initial treatment. [2] (10.1016/j.jhsa.2008.12.030)
  • [L4] [3] (10.1177/1758998315599796)
  • [L4] The authors believe the technique gives satisfactory medium-term results and should be considered part of the surgical treatment for de Quervain tenosynovitis. [4] (10.1055/s-0035-1556862)
  • [L3] Addressing misconceptions about de Quervain's tenosynovitis in terms of the consequences for patients and how long their symptoms will last should allow patients to make informed decisions about the treatment that best matches their values. [5] (10.1097/corr.0000000000001577)
  • [L4] Surgical release of De Quervain's tenosynovitis remains the gold standard treatment, and longitudinal incision offers advantage of easy identification of compartment, more complete releases of tendon sheath and peritendinous adhesions and less risk of palmar subluxation of tendons. [6] (10.1007/s12306-018-0585-1)
  • [L3] The practice of obtaining routine wrist radiography prior to surgeon evaluation is wasteful as patients do not benefit from the resulting radiologic data. [7] (10.1055/s-0037-1606124)
  • [L4] Providers should remain cognizant that patients presenting with de Quervain's tenosynovitis may favor initial nonsurgical management. [8] (10.1016/j.jhsg.2024.01.009)
  • [L4] [9] (10.1016/j.jhsa.2014.09.024)
  • [L4] Though considered as a manifestation of de Quervain's disease by some authors, styloid abnormalities do not affect the outcome of management as proved in this study. [10] (10.1007/s11552-010-9258-8)
  • [L4] [11] (10.1054/jhsb.1999.0277)
  • [L4] The release of the first extensor compartment for refractory de Quervain's disease resulted in good clinical outcomes with minimal morbidity. [12] (10.4055/cios.2014.6.4.405)
  • [L3] This study indicates that corticosteroid injections are a useful treatment for de Quervain's tenosynovitis, leading to treatment success 73.4% of the time within 2 injections. [13] (10.1177/1558944716681976)
  • [L1] Corticosteroid injection with a short duration of immobilization remains the primary and effective treatment for de Quervain tenosynovitis. [14] (10.1016/j.jhsa.2024.03.003)
  • [L3] [17] (10.1177/1753193415611414)
  • [L4] In cases with symptoms of de Quervain's syndrome where the constriction involves only the extensor pollicis brevis in a separate compartment, exploration of both compartments is advised. [18] (10.2106/00004623-194931040-00019)
  • [L1] One or two local injections of 1 ml triamcinolonacetonide 10 mg/ml provided by general practitioners leads to improvement in the short term in participants with de Quervain's tenosynovitis when compared to placebo. [19] (10.1186/1471-2474-10-131)
  • [L4] The presence of a septum does not significantly affect clinical outcomes or complications following endoscopic release for de Quervain's syndrome. [20] (10.1177/17531934231214137)
  • [L3] More negative perceptions of the consequences of de Quervain's tenosynovitis and worse pain catastrophizing are associated with worse pain and reduced function at baseline in patients awaiting surgical decompression of de Quervain's tenosynovitis. [21] (10.1097/corr.0000000000000992)
  • [L4] Patients who scored lower than 40 for physical function or higher than 60 for pain interference had significantly increased odds of eventually undergoing surgical release for de Quervain tenosynovitis. [23] (10.1016/j.jhsa.2023.07.005)
  • [L2] Although the success rate for the treatment of De Quervain's tenosynovitis decreases with multiple injections, repeat injections have a high rate of success and are a viable clinical option. [25] (10.1016/j.jhsa.2021.04.018)
  • [L1] [26] (10.1002/14651858.cd005616.pub2)
  • [L4] Patients with diabetes mellitus have a decreased probability of success following a single corticosteroid injection for de Quervain tenosynovitis in comparison to nondiabetic patients, but the effectiveness of each additional injection does not appear to diminish. [27] (10.1016/j.jhsa.2022.02.018)
  • [L4] Endoscopic release of the extensor compartment seems to be an effective and safe procedure in patients with de Quervain's disease who are unresponsive to nonoperative treatments, despite a little increase in operation time. [28] (10.1016/j.bjps.2011.05.015)
  • [L1] Pain and clinical outcomes significantly improved after corticosteroid injection in de Quervain's disease. [29] (10.1016/j.otsr.2019.11.015)
  • [L1] Endoscopic release for de Quervain's tenosynovitis seems to provide earlier improvement after surgery, with fewer superficial radial nerve complications and greater scar satisfaction, when compared with open release. [30] (10.1302/0301-620x.95b7.31486)
  • [L2] [31] (10.1016/j.jhsa.2008.08.020)
  • [L4] Most informed patients initially elect symptomatic treatment for de Quervain's disease, and most experience symptom resolution within one year. [33] (10.1007/s12593-009-0018-3)
  • [L2] [35] (10.1177/1753193412475043)
  • [L4] [37] (10.1055/s-0040-1716522)
  • [L3] [38] (10.1055/s-0038-1626690)
  • [L3] This finding may question the validity of using the asymptomatic thumb as a standard measure to identify the symptomatic thumb's impairments associated with de Quervain's disease. [39] (10.1197/j.jht.2008.03.004)
  • [L5] Ultrasound is a useful imaging technique for diagnosing de Quervain's disease and provides important information about anatomic variations within the first extensor compartment. [40] (10.1136/bcr-2021-242173)
  • [L4] Ultrasound is a worthwhile preoperative investigation in case of de Quervain's disease. [41] (10.1007/s12593-009-0001-z)
  • [L3] The prevalence of a septated first dorsal compartment is considerably higher than previously reported, most notably in patients with De Quervain tenosynovitis. [42] (10.1177/1558944718810864)
  • [L4] [43] (10.1177/0363546504268134)
  • [L4] In vivo EPB tendon excursion measures have been quantified, and wrist position has been found to have an influence on excursion. [44] (10.1016/j.jht.2017.12.004)
  • [L4] When it does, particularly in patients with de Quervain's disease, it is likely to reside in a subcompartment of the first dorsal compartment. [46] (10.1016/j.jhsa.2008.12.015)
  • [L3] Those subjects demonstrate a significant decrease in maximum velocity in slow fist tasks, highlighting the need for comprehensive assessment to ascertain the full extent of functional limitations that can occur in the setting of hand pathology. [48] (10.1177/1558944717729218)
  • [L2] The anatomical findings are consistent with previous studies, with an expectation to encounter the superficial branch of the radial nerve in more than 50% of patients. [58] (10.1055/s-0039-1688700)

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